Corneal Disorders and Amniotic Membrane Placement: Innovative Treatment Approaches

As constant innovation occurs in medical research to improve patient outcomes and life quality, one such groundbreaking therapy that has gained popularity in the field of optometry in recent years is amniotic membrane therapy (AMT) for ocular use. This surgical procedure can harness the regenerative and healing properties of the amniotic membrane to treat a wide range of ocular conditions effectively. Can AMT be effective for corneal disorders? Find out in detail in this article. Visit our clinic or check our website at to see all the services that can help you manage your eye condition.


Corneal health and disease symptoms

The cornea is the outer layer of the eye which is vulnerable to trauma, bacteria, and irritants such as allergens or chemicals. It is very dense with nerve fibers which make it very sensitive. So, any corneal abnormality can greatly affect its function and eye comfort.


Here are the common problems that affect corneal health:

  • Injury: Corneal abrasions can occur from objects such as glass or wood getting into the eye. Any direct trauma to the cornea from a foreign object such as metal or a chemical can cause a cloudy cornea or permanent corneal
  • Infection: Bacterial or viral infections such as conjunctivitis can cause discomfort and redness and may cause an inflamed cornea or even permanent corneal scarring.
  • Irritants: Allergens and certain chemicals in contact with the cornea cause itchiness and pain. Usually, symptoms related to irritants appear upon contact and may need urgent medical treatment.


Sometimes patients don’t even know that their visual problems are related to the cornea. If you experience any of these symptoms, you should seek immediate help from an eye specialist, including:

  • Itchiness
  • Redness
  • Intense pain
  • Burning
  • Sudden vision changes
  • Light sensitivity
  • Blurriness or cloudiness
  • A foreign body sensation in the eye


Indication for an AM Placement

There are many indications for Amniotic membrane placement for eye disorders. In this procedure, the doctor uses the amniotic membrane, which is the innermost layer of the placenta of healthy pregnant women. It is extracted during cesarean delivery from the placenta. It also has anti-inflammatory and immunomodulatory properties which can promote tissue healing, reduce inflammation, and prevent the tissue from infections. The most common conditions treated with AM placement are:

  • Corneal ulcers and infections: AMT is very useful in cases of non-healing or persistent corneal ulcers, providing an effective solution to promote healing and lower the risk of vision loss.
  • Dry eye disease: AMT can treat dry eye disease very effectively by alleviating symptoms and aiding in the healing of the ocular surface.
  • Refractive surgery complications: In case of corneal ectasia or refractive surgery complications, AMT can promote the healing process and reduce the risk of vision impairment.
  • Conjunctival reconstruction: AMT can be used for conjunctival reconstruction in patients with extensive conjunctival scarring or inflammation.


Benefits of AMT

There are many benefits AMT patients can enjoy for their eye health, including:

Reduced inflammation:

Inflammation is a major symptom that occurs in many ocular diseases and conditions. The amniotic membrane contains anti-inflammatory cytokines and growth factors, which can reduce inflammation and promote healing. This is the reason it has become an excellent adjunctive therapy for patients with dry eye disease, conjunctivitis, and other inflammatory ocular conditions.

Improved tissue regeneration:

The amniotic membrane contains growth factors and cytokines that promote the regeneration of damaged tissue, which is particularly useful in treating chronic wounds and ulcers.

Pain relief and comfort:

Patients with severe ocular surface disorders often experience severe discomfort and pain. AMT showed significant pain relief by promoting healing and reducing inflammation, providing comfort, and improving the patient’s life quality.

Scar prevention and reduction:

Scaring can impact vision and overall ocular health. AMT can reduce scarring after trauma, surgery, or corneal infections because the amniotic membrane can promote the wound-healing process which preserves the integrity of the tissues.

  1. Low risk of complications:

As the Amniotic membrane transplantation procedure uses graft, it carries a low risk of adverse reactions or complications. The processing and preservation techniques employed in modern AMT products ensure that they eliminate infectious agents while retaining the tissue’s therapeutic properties.


Amniotic membrane placement for corneal disorders is a good option because this surgical procedure is new and offers many benefits such as promoting healing, and tissue regeneration, preventing and reducing scarring, infection, and inflammation, and low risk of complications. Your recovery depends on the type and severity of your eye condition. You can talk with your eye specialist to discuss its benefits and risks for your condition and to decide whether this treatment option is good for you or not.


If you need professional help with your eye problems, visit our ophthalmology clinic in Brooklyn where the best eye specialists can examine your eyes properly and provide you with the best treatment for your eyes. Call us to book your appointment now!

At Doral Health and Wellness Ophthalmology Center, our eye doctors can help you recover from all types of eye conditions and diseases. To schedule an appointment, please call us at 1-347-384-5690 or visit us at 1797 Pitkin Avenue, Brooklyn, New York 11212. You can also visit our website at