Prostate Biopsy Procedure: Step-by-Step Guide and Patient Considerations

The prostate is a small, walnut-sized gland located below your bladder and in front of a male’s rectum. It is an integral part of the male reproductive system and serves several functions, which can include:

  • Producing fluid for the semen
  • Preventing the urine to be included during ejaculation


If you are looking for a clinic near you that offers prostate biopsy procedure, you can visit us at Doral Health and Wellness Urology Center, we have the best urologist that can help you understand how the procedure is done. You can contact us by visiting our clinic or visiting our website at or


If your medical provider suspect or has concerns about prostate cancer based on your other diagnostic tests, a prostate biopsy may be recommended. Prostate biopsy is not part of a routine screening but will only be recommended based on specific indications.


A prostate biopsy is a medical procedure in which small samples of tissue are taken from your prostate gland, to be examined under a microscope. This procedure is commonly performed when there are concerns about prostate cancer based on elevated levels of prostate-specific antigen (PSA) in your blood, abnormal results from a digital rectal exam (DRE), or other diagnostic indications.


Here’s an overview of the prostate biopsy procedure:


  • Transrectal Ultrasound (TRUS) — Before the biopsy, a transrectal ultrasound may be used to provide a clear image of your prostate gland. This imaging will help guide the biopsy needle to specific areas of your prostate.


  • Local Anesthesia — Local anesthesia is typically administered to numb the area around your prostate, which can reduce discomfort during the procedure.


  • Biopsy Needle Insertion — A thin, hollow needle is then inserted through the wall of your rectum into your prostate gland.


  • Sample Collection — Small samples, known as biopsy cores, are taken from different areas/spots of your prostate using the biopsy needle. The number of cores collected can vary but is usually around 10 to 12.


  • Pathology Examination — The collected tissue samples are sent to a pathology laboratory, where they are analyzed under a microscope. This examination determines whether cancer cells are present and, if so, to assess the grade and extent of your cancer.


  • Post-Biopsy Care — After the biopsy, you may experience some discomfort, and there may be temporary blood in your urine or semen. Care instructions will be provided by your medical provider for your post-biopsy period.


  • Results and Further Management — Your biopsy results will be the guide for further decisions about the management of your prostate’s health. If cancer is detected, additional tests may be conducted to determine the stage of the cancer and plan appropriate treatment.


It is essential to discuss the potential benefits and risks of a prostate biopsy with your medical provider or urologist. The decision to undergo a biopsy should be based on your overall health, risk factors, and a thorough understanding of the potential implications of the procedure.


If you experience symptoms of problems in your prostate, talk to a medical provider that could help with the proper diagnosis of your condition. Further diagnostic tests may be recommended and/or a prostate biopsy procedure may be needed. You can schedule an appointment with Doral Health and Wellness Urology Center’s best urologist in Brooklyn and inquire about how a prostate biopsy is done. Our specialists will work with you and help you understand how this procedure is done. To schedule an appointment, please visit us at 1797 Pitkin Avenue, Brooklyn, New York 11212 or call 1-347-384-5690. You can also visit our website at