Syndrome of inappropriate antidiuretic hormone (SIADH)

Are you suffering from cramps and vomiting? If yes, you might be suffering from the syndrome of inappropriate antidiuretic hormone (SIADH).  

This happens when your body produces too much antidiuretic hormone, which results in too much water storage in the kidneys. It can be dangerous in some cases because it can lead to coma and seizure. So, if you notice the symptoms, talk to your doctor to avoid these complications. Keep reading this article to get an insight into the syndrome of inappropriate antidiuretic hormones. 

Syndrome of inappropriate antidiuretic hormone (SIADH) is a condition where the body produces too much antidiuretic hormone (also known as vasopressin) in the bloodstream. This hormone regulates the function of the kidneys to store water in the body, and its release in the form of urine.  


SIADH is common in people who are suffering from heart failure or have a diseased hypothalamus (where the antidiuretic hormone is produced, and it directly affects the pituitary gland where this hormone is stored and released). Some types of cancers also lead to the formation of this hormone elsewhere in the body (such as lung cancers).  

Other causes that affect its production include: 

  • Encephalitis (causes inflammation in the brain). 
  • Brain tumors 
  • Meningitis (inflammation of the membranes that cover the brain and spinal cord). 
  • Psychosis 
  • Head trauma 
  • Guillain-Barre syndrome (a condition that affects nerves of the brain).  
  • Head trauma 
  • Lung diseases 
  • Certain medications such as seizure drugs, cancer drugs, antidepressants, and other types of drugs are used to treat conditions like diabetes and blood pressure, etc.  
  • Any surgery that damages the hypothalamus or pituitary gland 
  •  HIV 
  • Thyroid or parathyroid deficiencies  
  • Hereditary causes 
  • Disorders of the brain such as injury, infections, or stroke 
  • Mental disorders 


SIADH symptoms can range from mild to severe depending on the cause. This condition makes it difficult to release water and your urine will be concentrated. This can also lower your sodium levels in the body.  

Other severe symptoms you might notice such as:  

  • Muscle weakness 
  • Nausea and vomiting 
  • Cramps  
  • Tremors 
  • Mood impairment such as being depressed or irritable.  
  • Confusion or hallucinations 
  • Memory problems or changes in behavior 
  • Seizures 
  • Coma 
  • Stupor 
  • Loss of appetite  

These symptoms also resemble other health conditions, so it is important to consult with the doctor to get a diagnosis to confirm your condition.
Having elevated levels of this hormone leads to storing excess amounts of water in the body which results in cramps, muscle weakness, vomiting, and in severe cases can lead to seizures and coma.  

So, you can avoid this condition by noticing the symptoms and taking the treatment. Treatment depends on what causes this condition but the baseline treatment in every case is restricting the amounts of fluid intake.  

Want to know what treatment is best for SIADH? At Doral Health and Wellness, we have doctors that can help you manage your condition. For more information, you can visit us at 1797 Pitkin Avenue, Brooklyn, New York, 11212, or call us on 1-347-384-5690. You can also visit our website at or contact us at if you have any queries.